2011 AES Annual Meeting - 401.01 - Merritt-Putnam Symposium: Sleep and Epilepsy
Program Length: 180 minutes
There is a dynamic symbiotic relationship between sleep and epilepsy. In many patients, seizures occur only during sleep, and many patients with epilepsy have disturbed sleep. This symposium will examine the relationship between sleep and epilepsy. The symposium will begin with a review of the clinical and electroencephalographic features of nocturnal seizures and nonepileptic parasomnias. This talk will be followed by a discussion of the effect of epilepsy on sleep and the effect of sleep disorders on epilepsy. The basic neurophysiological and neurochemical mechanisms responsible for increased seizure susceptibility during sleep will then be reviewed. The consequences of nocturnal seizures on memory consolidation are substantial and the adverse effects of nocturnal seizures will be described. During the past few years much has been learned about the treatment of nocturnal seizures and epileptiform discharges and the symposium will conclude with a discussion of current treatment options of nocturnal seizures.
- Identify distinguishing clinical and electroencephalographic (EEG) features of nocturnal seizures and parasomnias which allow accurate diagnosis
- Make decisions which improve patient response to treatment based on an understanding of how sleep disturbances can exacerbate epilepsy and epilepsy can adversely alter sleep
- Apply acquired understanding of the physiological mechanisms of sleep and epilepsy in managing patients with both sleep disorders and seizures
- Use data provided to recognize the consequences of nocturnal seizures and epileptiform discharges on cognition and appropriate strategies to ameliorate the impact
- Manage nocturnal seizures and epileptiform activity using current treatment options.
Basic and Intermediate (see page 98 for details)
Chair: Gregory L. Holmes, M.D.
Introduction and Overview
Gregory L. Holmes, M.D.
Differentiating Nocturnal Epilepsy Form Parasomnias
Jennifer L. DeWolfe, D.O.
The Epilepsy-Sleep Connection: How Sleep Disorders Influence Management of Epilepsy and Epilepsy Treatments Impact Sleep
Beth A. Malow, M.D.
Neurobiological Mechanisms Linking Sleep and Epilepsy
John Huguenard, Ph.D.
Sleep, Memory, and Learning: The Impact of Epilepsy
Robert Stickgold, Ph.D.
Treatment of Nocturnal Seizures: Are We Still in the Dark?
Blaise F. D. Bourgeois, M.D.
Gregory L. Holmes, M.D.