Archived AES Symposia 2006
AET Symposium - Antiepileptic Drug Development: The New Frontiers
Program Length: 2 hrs 13 min
The purpose of this symposium is to critically review the process by which new antiepileptic drugs (AEDs) are developed. The emphasis will first be on recent and potential improvements in the experimental models for selection of new compounds. Existing and potentially better trials for pre-marketing clinical development will be discussed. This will be followed by a critical review of how AEDs that are currently in development have been tested so far, and could be tested further. Finally, there will be a discussion of the optimal use and assessment of new AEDs once they are approved for marketing.
At the conclusion of this activity, participants should be able to:
- Identify improved and needed experimental methods for selection of new antiepileptic compounds
- Name existing and improved clinical trial methods for new AEDs
- Name AEDs currently in development and identify how they have been developed so far
- Identify and apply methods for better use and assessment of current and future newly marketed drugs.
The symposium is designed for neurologists, pharmacists, nurses, neuroscientists, neurosurgeons, and other healthcare professionals involved in the care of patients with epilepsy or who carry out research in epilepsy.
Cochairs: Blaise F. D. Bourgeois, M.D., Tracy A. Glauser, M.D., H. Steve White, Ph.D.
Opening Remarks Blaise F. D. Bourgeois, M.D.
Improving Experimental Models
H. Steve White, Ph.D. and Karen S. Wilcox, Ph.D.
Pre-Marketing Clinical Development Strategies
Tracy A. Glauser, M.D.
AEDs Currently in Development: A Critical Review
Emilio Perucca, M.D., Ph.D.
How Should AEDs Be Used and Assessed After Marketing?
Jacqueline A. French, M.D.
Disclaimer: Opinions expressed with regard to unapproved uses of products are solely those of the faculty and are not endorsed by the American Epilepsy Society or any manufacturers of pharmaceuticals.