Neuropharmacology

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Thanks to Dr. Luisa L. Rocha for the Spanish translations.

Neuropharmacology Section PDF of Text and Slides combined  June 2011

Spanish - Text and Slides

Neuropharmacology Section Power Point Slides    June 2011

Spanish - Slides

Neuropharmacology and Neurosurgical Sections - Self Test

Table of Contents

I     Definitions

  • Seizure vs. Epilepsy
  • Antiepileptic drugs

II    History of antiepileptic drugs (AEDs)

III   AEDs: Molecular and cellular mechanisms

IV    Cellular mechanisms of seizure generation

V     Pharmacokinetic principles

  • Drug metabolism enzymes
  • AED inducers
  • AED inhibitors
  • AED Serum Concentrations
  • Definitions: Therapeutic Index, Steady state
  • Pharmacodynamic interactions

VI    Comparative pharmacokinetics of old vs. new AEDs

VII   Pharmacokinetics in special populations

VIII  Metabolic changes of AEDs

IX     AEDs and drug interactions

X      Adverse effects

  • Acute vs. chronic
  • Idiosyncratic

Case Studies