Read the latest medical research on epilepsy and seizures including new treatments and potential cures under development.
Updated: 1 hour 30 min ago
Researchers have identified areas of the human brain in which breathing is controlled and, in some cases, impaired. Sudden unexpected death in epilepsy is becoming increasingly recognized as a very real and devastating problem in which impaired breathing is thought to play a critical role. Researchers believe breathing may be impaired during and after seizures, without the patient's knowledge.
A breakthrough discovery is expected to help thousands of young girls worldwide who are suffering from a rare yet debilitating form of epilepsy, an international team led by a genetics expert reports.
A small fraction of pregnancies occur in women with epilepsy but a new study suggests those women may be at higher risk for complications and death during delivery, in a new article.
While many people with epilepsy can control their seizures with medication, those unpredictable and involuntary changes in behavior and consciousness can be limiting for others. Neurologists evaluated the application of smartphones in epilepsy care. Apps include seizure diaries as well as medication trackers with reminders to take the next dose of medication. In addition, apps are available to answer any questions patients with epilepsy might have, to detect potential drug interactions and to detect seizures.
Epilepsy and tinnitus are both caused by overly excitable nerve cells. Healthy nerves have a built-in system that slams on the brakes when they get too excited. The 'brakes' are actually potassium channels that regulate nerve signals. A new drug may treat both conditions by selectively opening potassium channels in the brain.
An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study. In a series of experiments, the amino acid D-leucine, found in many foods and certain bacteria, interrupted prolonged seizures, a serious condition known as status epilepticus, and it did so just as effectively as the epilepsy drug diazepam -- the choice of treatment for patients in the throes of convulsions -- but without any of the drug's sedative side effects.
A new study has taken the first-ever look at the academic outcomes of children with epilepsy who have had brain surgery, and found that they have a higher chance of struggling in class following their surgery.
The mission of neural stem cells located in the hippocampus, one of the main regions of the brain, is to generate new neurons during the adult life of mammals, and their function is to participate in certain types of learning and responses to anxiety and stress. New research has discovered that hippocampal neural stem cells in the case of epilepsy stop generating new neurons and are turned into reactive astrocytes, a cell type that promotes inflammation and alters communication between neurons. Now the researchers are exploring the potential of neural stem cells in future therapies to fight the disease.
Epilepsy patients undergoing intracranial monitoring for seizure localization provide an excellent model to study discharge patterns of single neurons within the mesial temporal lobe during memory tasks. Animal models have shown that discharge patterns of CA3 neuronal populations influence the discharge of CA1 neurons. The researchers hypothesized that human hippocampal neurons have regionally and temporally specific and interrelated discharge patterns, which contribute to task specific memory formation and retrieval.
Parents describe arduous journey to pediatric epileptic surgery when their child's disease becomes resistant to anti-seizure meds
Now, parents share their arduous and “circuitous” journey to get referrals for pediatric epilepsy surgery once their child’s disease stops responding to anti-seizure medications. The study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.
A new guideline found that administering an antiepileptic medication immediately after a first seizure reduces the risk of having another seizure within two years.
Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies suggest that epileptic seizures impair the neural pathways needed for socialization, but the details of this process remain unclear.
For a condition such as epilepsy, it is essential to act at exactly the right time and place in the brain. For this reason, a team of researchers has developed an organic electronic micropump which, when combined with an anti-convulsant drug, enables localized inhibition of epileptic seizure in brain tissue in vitro.
A medicinal liquid form of marijuana may show promise as a treatment for children with severe epilepsy that is not responding to other treatments, according to a new study.