Read the latest medical research on epilepsy and seizures including new treatments and potential cures under development.
Updated: 2 hours 8 min ago
A new study indicates that US doctors appear to have reached an unexpected consensus about which anti-seizure medicine to prescribe to their pediatric patients.
A unique metabolic signature associated with epileptic brain tissue that causes seizures has been identified by researchers. It will allow physicians to precisely identify small regions of abnormal brain tissue in early-stage epilepsy patients that can’t be detected today using current technology, they say.
Researchers show that the neurons of mice undergoing seizures fire off in a sequential pattern no matter how quickly the seizure propagates -- a finding that confirms seizures are not the result of neurons randomly going haywire.
People with damage to a crucial part of the brain fail to recognize facial emotions, but they unexpectedly find faces looking sideways more memorable researchers have found.
Increased levels of a micro-RNA could have a protective effect that explains why identical stressors trigger seizures in some people but not in others.
Children with Dravet syndrome, a severe form of epilepsy, had fewer seizures after taking a daily oral solution of the cannabis compound called cannabidiol, which does not have the psychoactive properties of marijuana, results from a double-blind, placebo-controlled trial reveal.
Although cannabis had been used for many centuries for treatment of seizure disorders, medical use became prohibited in the 20th century. However, with the loosening of laws regarding medical marijuana, research and clinical use of marijuana-derived substances are increasing. This has prompted the publishing of an in-depth assessment of the potential of cannabinoids for the effective treatment of epilepsy. Cannabinoids are components of the cannabis plant.
A computational approach could enable more patients with epilepsy to benefit from surgery when medications do not help, report investigators.
Investigators have identified silent, seizure-like activity in the hippocampus -- a brain structure significantly affected in Alzheimer's disease -- in two patients with Alzheimer's disease and no known history of seizures. These alterations in the brain's electrical activity could not be detected by standard EEG readings and primarily occurred during sleep, a time when memories are consolidated.
Little is known about which specific areas of the brain contribute to a patient's epileptic network or the roles these different areas play. As a group of researchers now reports one way to get closer to the complex wiring of the human brain is by merging concepts from a timed-based synchronization theory and space-based network theory to construct functional brain networks.
A 15-year follow-up study of young adults with epilepsy found that those with uncomplicated epilepsy who were seizure-free for five years or more did as well as their siblings without epilepsy in measures of education, employment, family arrangements and driving status. Youth with complicated epilepsy had worse social outcomes and were less likely to drive, even if living without seizures.
Taking cannabidiol may cut seizures in half for some children and adults with Lennox-Gastaut syndrome (LGS), a severe form of epilepsy, according to new information from a large scale controlled clinical study. Cannabidiol is a molecule from the cannabis plant that does not have the psychoactive properties that create a 'high.'
Consider two children who have childhood absence epilepsy (CAE), the most common form of pediatric epilepsy. They both take the same drug -- one child sees an improvement in their seizures, but the other does not. A new study has identified the genes that may underlie this difference in treatment outcomes, suggesting there may be potential for using a precision medicine approach to help predict which drugs will be most effective to help children with CAE.
The relationship between stress and seizures has been well documented over the last 50 years. A recent review article looks at the stress-seizure relationship and how adopting stress reduction techniques may provide benefit as a low risk form of treatment.