Read the latest medical research on epilepsy and seizures including new treatments and potential cures under development.
Updated: 1 hour 55 min ago
A specific diet can be used to help treat patients with uncontrolled epilepsy, a new study indicates. The findings reveal how the ketogenic diet acts to block seizures in patients with drug-resistant epilepsy.
Specific forms of epilepsy may manifest as early as in the first weeks of life. A new laboratory study shows that a preventive therapeutic strategy can be successful if it is applied within a time window critical to brain development.
In epilepsy, nerve cells or neurons lose their usual rhythm, and ion channels, which have a decisive influence on their excitability, are involved. A team of researchers has now discovered a new mechanism for influencing ion channels in epilepsy. They found that spermine inside neurons dampens the neurons excitability. In epilepsy, spermine levels decrease, causing hyperexcitability. The researchers hope that their findings can be exploited to develop new therapies for epilepsies.
Researchers conducted experiments on the hippocampus of neonatal rats and mice, quite similar to the one of a human fetus at the second half of pregnancy period. Hence it will be possible make precise identification of medicaments safe for a fetus and its brain development. The potential application of obtained results is to find its place in treating brain malfunctions, such as epilepsy, post-ischemic conditions, and brain traumas.
A revolutionary new research approach has for the first time shown that epilepsy could be preventable. However, the technique developed and tested over three-years will not benefit individuals who already have epilepsy, scientists say.
Although the absolute risk was low, researchers found an increased risk of childhood-onset epilepsy among children in Denmark who had a hospital-diagnosed pertussis infection, compared with the general population, according to a study.
Scientists have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.
A gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease has been discovered by a group of researchers.
A potential new class of drugs has been discovered in mice studies that may prevent the development of temporal lobe epilepsy, one of the most common and devastating forms of epilepsy.
For children with rare genetic disorder, more extensive epilepsy surgery yields better seizure control
Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery.
One-third of epilepsy patients have seizures that are not controlled by medications. In addition, one-third have brain lesions, the hallmark of the disease, which cannot be located by conventional imaging methods. Researchers have piloted a new method using advanced noninvasive neuroimaging to recognize the neurotransmitter glutamate, thought to be the culprit in the most common form of medication-resistant epilepsy.
Scientists have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory.