Infrastructure Grants

AES Infrastructure Grants facilitate the creation of national or international multicenter research programs. Proposals are welcomed across the spectrum of epilepsy research, including basic, translational, and clinical research methodology to study epilepsy, seizures, and related disorders.

Each grant will provide financial support for organizational planning sessions, infrastructure development, and/or pilot projects to enable the research program to compete for subsequent investment by other organizations. The program is a revival, with some modifications, of a funding program that had been offered from 2006-2014.

Infrastructure Grants provide up to $50,000 for one year. Each grant may be renewed up to one time through competitive application, with no guarantee of renewal. The number of awards made each year is contingent on available funds. Allowable costs include the direct costs of research, travel and meeting costs, and staff or administrative costs that are directly applicable to the proposed work. Indirect or F&A costs are not covered, as the modest seed funds from this grant are to help investigators compete for the larger grants that cover the full costs of research.

ANNUAL APPLICATION DEADLINE

April 15, 2020

Funding decisions will be announced within eight weeks of the application deadline.

ELIGIBILITY CRITERIA

  1. The contact principal investigator(s) should be members of the American Epilepsy Society
  2. The contact principal investigator should be at an academic research institution in the United States. Collaborators may be based at international academic research institution as well as at non-profit or for-profit organizations.
  3. Proposals should outline the one-year and the long-term goals for creating a multicenter research program to hasten the speed of discovery. Examples of eligible goals include, but are not limited to, establishing centralized databases, common protocols, shared resources, core laboratories, and exchange of rapidly developing techniques and technologies to collect and analyze large scale data.
  4. Applications should include a minimum of three collaborators across three institutions.

APPLICATION INSTRUCTIONS

The following application materials must be submitted as a single compiled PDF to grants@aesnet.org by 11:59pm ET on the date of the deadline.

  1. Completed cover sheet with basic information about the applicants, institution, and appropriate institutional signatures
  2. Plan of activities (5 pages maximum, excluding references) to include
      • An abstract or specific aims overview
      • Background/significance
      • Preliminary results (if any)
      • Research plan, including the respective roles of each center. It should also include a statement of the intended roles of each PI and center to the intended organization and its research administration
      • Plans for future funding
  3. Biosketches (NIH style) for major PIs and other key personnel whose expertise or background will be essential to the project
  4. Letter of commitment from each site PI
  5. Budget (two-page maximum, no template provided). Allowable costs include the direct costs of research, travel and meeting costs, and staff or administrative costs that are directly applicable to the proposed work. Indirect or F&A costs are not covered because the modest seed funds from this grant are to help an investigative team to compete for the larger grants that cover the full costs of research.
  6. Animal care and/or IRB approval as appropriate. If not available at the time of the initial application, these must be submitted before the award is made.

REVIEW PROCESS AND CRITERIA

Infrastructure Grants are reviewed by the AES Research and Training Council with focus on the following criteria.

  1. Fit for Infrastructure: Does the proposal meet the criteria of an Infrastructure grant as a new multicenter research program with a minimum of 3 or more institutions, with the potential to catalytically advance epilepsy research with new infrastructure, tools, or other resources?
  2. Investigators & Environments: Does the investigative team have the resources, staff, and qualifications to carry out the proposed work?
  3. Budget & Workplan: Is the budget appropriate for the proposed workplan? Is the proposed workplan feasible and appropriate for a one year $50,000 award?
  4. Support for the next generation. AES encourages but does not require inclusion of early career investigators as active participants in the proposed multicenter research program
  5. The research plan, including the strength of the scientific premise, the potential for innovation and significance to the scientific understanding and clinical care of patients with epilepsy
  6. Will the proposed research take place, at least in part, at U.S. Institutions? Preference will be given to applications that will strengthen U.S.-based research through national or international collaboration. If a non-academic institution is included, a justification should be added.

Questions or eligibility inquiries? Contact grants@aesnet.org