Abstracts

To determine the efficacy of Leviteracetam (LEV) in the control of clinical convulsive crisis in the epilepsies or epileptics syndromes in children. Although Levetiracetam has been only approved for adults, it has showed to be effect in children., Between September 2002 and January 2005, twenty-four chil-dren of our unit were treated with Levetiracetam (40-50 Mg/Kg/day) . Our retrospective-analytic study was carried out in fifteen patients (age: 12 months [ndash] 13 years). All patients had their crisis diary checked before and after the addition of Levetiracetam. The follow up was from 8 to 26 months (average 15 months). The patients were classified in three groups, according to the 1989 ILAE classification. The reduction of crisis was rated in percentage (%)., We had seven idiopathic syndromes, three symptomatic syndromes and five cryptogenic syndromes. We had eight patients with partial epilepsies and seven patients with generalized epilepsies. All groups showed significant reduction of epileptic crisis (70% in more than 65% of patients). We observed no severe significants adverses reactions. In all patients the levetiracetam was add to polytherapy., The fact of making a correct diagnosis of the epileptics syndromes goes in favor of taking a better therapy choice. The reduction of frequency of crisis was significant. It was shown that Levetiracetam has a wide range of action.,