Clinical Guidance

The American Epilepsy Society is a trusted source of evidence-based clinical guidance for epilepsy specialists and other healthcare providers. 

This page provides links to information about AES processes for systematic review and clinical guidance development, as well as epilepsy-related resources such as guidelines, practice parameters, and other clinical guidance developed by AES, other societies, or collaboratively.

AES Clinical Practice Guideline Development Manual (2020)
This manual outlines principles and processes intended to guide AES-led workgroups in the development of high-quality clinical guidance products consistent with broadly-accepted, evidence-based principles and processes appropriate to the needs of the epilepsy clinical community.

AES Clinical Guidance in Development

  • AES/ACNS Electrocorticography (ECoG) Systematic Review and Guideline
  • AES/AAN/CNS Epilepsy Surgery Systematic Review and Guideline



Evidence-based Guidelines


Practice Parameters


Additional Resources