Abstracts

Rationale: IDENTIFYING FOCAL NEUROIMAGING ABNORMALITIES MAY LEAD TO FOCAL SURGICAL RESECTIONS AND POSSIBLE CURES FOR MEDICALLY INTRACTABLE AND DISABLING EPILEPSY. THIS ABSTRACT HIGHLIGHTS 3 SUCH CASES AND CHARACTERIZES THE CLINICAL AND NEUROIMAGING FINDINGS IN THESE CASES. Methods: A RETROSPECTIVE DESCRIPTIVE STUDY OF 3 CASES WITH SUBTLE CORTICAL GYRAL ABNORMALITIES WHO UNDERWENT FOCAL SURGICAL RESECTIONS OF THESE REGIONS AFTER INVASIVE EEG MONITORING OR ELECTROCORTICOGRAPHY WHO WERE CURED OF THEIR EPILEPSY WILL BE PRESENTED. Results: FOCAL CORTICAL DYSPLASIAS MAY PRESENT WITH SUBTLE GYRAL ABNORMALITIES. THESE CORTICAL GYRAL ABNORMALITIES MAY GUIDE INVASIVE EEG OR ELECTROCORTICOGRAPHY AND MAY DELINEATE SEIZURE ONSETS WITH PRECISION. RESECTION OF THESE AREAS RESULTS IN EXCELLENT SURGICAL OUTCOMES. Conclusions: SUBTLE CORTICAL GYRAL ABNORMALITIES MAY BE ASSOCIATED WITH INTRACTABLE EPILEPSY AND SEIZURE ONSETS. FOCAL RESECTION AFTER APPROPRIATE EVALUATION IN SELECTED PATIENTS MAY BE CURATIVE.