The Effect of Previous Surgery and Residual Pathology on the Efficacy of Vagus Nerve Stimulation.
Abstract number :
2.218
Submission category :
Year :
2000
Submission ID :
1269
Source :
www.aesnet.org
Presentation date :
12/2/2000 12:00:00 AM
Published date :
Dec 1, 2000, 06:00 AM
Authors :
Charles E Polkey, Michael Koutrimandos, Bhupal Chitnavis, Colin D Binnie, Kings Coll Hosp, London, United Kingdom.
RATIONALE: To investigate the effect of previous surgery and residual pathology on the effectiveness of vagus nerve stimulation METHODS:41 patients were available from 49 implanted between May 1995 and April 1999. 27 had no localised intracranial pathology and no previous surgery, 8 patients had previously undergone resective surgery and a further 6 had residual pathology, 3 after surgery. Sezure control at 6/12 and 12/12 after implantation was compared with baseline. RESULTS: Considering all seizure types 8/40 had a 50% or more reduction at 6/12 and 8/27 at 12/12. For cps the figures were 17/37 at 6/12 and 16/30 at 12/12. There was no difference, using a ?2 test between the groups CONCLUSIONS: Vagus nerve stimulation is effective in reducing seizure frequency but this effect is not influenced by previous resective surgery or residual pathology