Abstracts

Rationale: Status epilepticus in children is an important public health problem. It is associated with significant morbidity and mortality. It is insidence of between 17 and 23 per 100 000 children per year. Children status epilepticus (CSE) is defined as either two or more convulsions without complete recovery of consciousness between seızures ( intermittent CSE) or as a single prolonged seizure that last at least 30 min (continuous CSE). Effective treatment of the seizures requires early and robust pharmacological intervention and recognition of the predictors of prolonged seizures that can be modified. We aimed to define clinical and demographic data of the our patients with status epilepticus Methods: We investigated the etiology, magnetic resonance, electroencephalography duration of the seziure, treatment and prognosis of patients hospitalized for status epilepticus at our pediatric intensive care unit. Our records of 39 cases admitted to hospital with status epilepticus were reviewed retrospectively between September 6,2011, and September 4,2013. While evaluating study data SPSS (Statistical Package for Social Sciences) Windows 15.0 program was used for statistical analysis. Results: Patients ranged in age from 3 months to 13 years.There were 16 (41%) girls and 23 (59%) boys. Their etiologies were chronical diseases in 22 (56,4%) (children with epilepsy or cerebral palsy), acute symptomatic in 8(20,5%)( trauma, intracranial infection, electrolyte imbalance ) febril in 7 (17,9%), unknown in 2 (5,1%). Seziure durations ranged from 30-60 minutes in 32 patients, whereas 7 manifasted refractory seziures longer then 60 minutes . Seizure termination is achieved by pharmacotherapy (benzodiazepines, phenytoin, valproate, anesthetic agents). Rectal diazepam was administered to 7 patients before admitted to hospital by their parents. Conclusions: Length of intensive care unit was longer than 24 hours in 15 patients. There was no mean the seziures duration between the length of intensive care unit. Brain edema was detected in 6 (15,4%). 4 patients with brain edema were dead. The mortality rate was 10,3%. There was a statically significant between treatment and mortality. None of the patients who died were administration prehospital treatment. Prehospital rectal diazepam administration and the treatment of brain edema in the intensive care unit may be useful in the management our the patients with status epilepticus.